Medication review brief · for the pharmacist
Omar Pelletier
95 · male · Hypertension
Prepared by Domino · Oct 1, 2026
Summary
1 likely prescribing cascade link. If Hydrochlorothiazide were reviewed, up to 1 downstream medicine might no longer be needed (2 → 0).
Question 1
Could the gout be from the diuretic raising uric acid? A different antihypertensive may be an option.
- Hydrochlorothiazide (Apr 25, 2025) → gout or high uric acid → Allopurinol (Jul 19, 2025) · likely 0.99 · study
If reviewed: Allopurinol; medicines 2 → 0; anticholinergic burden 0 → 0; fall-risk drugs 1 → 0.
Medicines
| Medicine | Started | Charted for | Domino |
|---|---|---|---|
| Hydrochlorothiazide as prescribed Dr. A. Patel (family doctor) | Apr 25, 2025 | Hypertension | Root of a cascade Beers-listed |
| Allopurinol as prescribed Dr. R. Ahmed (walk-in clinic) | Jul 19, 2025 | Gout / hyperuricaemia | Possibly treating a side effect |
Evidence
- Rochon PA, Gurwitz JH. The prescribing cascade revisited. Lancet. 2017;389(10081):1778-1780.
Decision support only. Domino flags patterns in a synthetic record for a clinician to review; it does not diagnose, and it never recommends stopping or changing a medicine. Synthetic data; no real patient.