Loading the patient’s graph
90 · female · Hypertension, Parkinson's disease, Type 2 diabetes, Anxiety
Root drug · likely · score 0.74
Feedback loop
Donepezil can cause insomnia, which Lorazepam treats; Lorazepam can cause cognitive impairment, which Donepezil treats. Each drug can feed the problem the other is treating.
Why Domino thinks so
Lorazepam started Sep 7, 2023 · Donepezil started Mar 3, 2024
Benzodiazepine → memory problems → dementia medication
Evidence: expert consensus
Not confirmed in the Irish national data (a significant negative association).
Question for the pharmacist: Could the memory problems be from the benzodiazepine? Benzodiazepines impair memory and attention in older adults.
Teach Domino. Your decision becomes memory every future review respects.
Checked and set aside
Analysis: 13 FalkorDB queries, run in parallel, 402 ms