Root drug · likely · score 0.89
Also feeding this chain: Gabapentin → ankle and leg swelling → Torsemide (possible, 0.40); Furosemide → leaking urine, urgency → Oxybutynin (possible, 0.29); Dimenhydrinate → confusion or memory problems → Rivastigmine (possible, 0.26).
Root drug · possible · score 0.42
Also feeding this chain: Metoprolol → dizziness or spinning → Dimenhydrinate (possible, 0.26).
Feedback loop
Dimenhydrinate can cause cognitive impairment, which Rivastigmine treats; Rivastigmine can cause nausea, which Dimenhydrinate treats. Each drug can feed the problem the other is treating.
Rivastigmine can cause urinary incontinence, which Oxybutynin treats; Oxybutynin can cause cognitive impairment, which Rivastigmine treats. Each drug can feed the problem the other is treating.
Why Domino thinks so
Torsemide started Apr 7, 2025 · Oxybutynin started May 2, 2025
Diuretic → urinary incontinence → bladder medication
Evidence: expert consensus
Not confirmed in the Irish national data (a significant negative association).
Question for the pharmacist: Could the urgency or leaking be from the diuretic? Changing the timing of the dose can help before adding a bladder medication.
Teach Domino. Your decision becomes memory every future review respects.
Checked and set aside
Analysis: 10 FalkorDB queries, run in parallel, 39 ms